Nicolier C, Kerber D, Bissoto A, Ben Bader S, Koch LM, Künzler J, Hossmann S, Rothenbühler M, Laimer M, Witthauer L.Alignment-free convolutional neural network classification of glycemic states in type 1 diabetes from GC–IMS breath spectra.Scientific Reports
(2026).
doi:10.1038/s41598-026-64471-2
Scattolo BM, Nicolier C, Balmer ML, Witthauer L.Clinical applicability of breath measurements for detecting disturbances in systemic glucose metabolism: a systematised review.Journal of Breath Research
(2026).
doi:10.1088/1752-7163/aea638
Pleus S, Eichenlaub M, Dabla PK, Diem P, Eriksson Boija E, Fokkert M, Hinzmann R, Jendle J, Klonoff DC, Lu J, Makris K, …, Witthauer L, et al.Clinical assessment and acceptance criteria for continuous glucose monitoring (CGM) system performance: A proposed guideline by the IFCC Working Group on CGM.Clinica Chimica Acta 580, 120728
(2026).
doi:10.1016/j.cca.2025.120728
Nicolier C, Rothenbühler M, Balmer ML, Witthauer L.Daytime circadian patterns of exhaled volatile organic compounds in adults without and with type 1 and type 2 diabetes: protocol for an exploratory observational study.BMJ Open 16(4), e113892
(2026).
doi:10.1136/bmjopen-2025-113892
Zwicky J, Fehr D, Albert I, Lehmann S, Witthauer L, Bonmarin M.Multimodal optical system for quantitative discrimination of bilirubin species.Biomedical Optics Express 17(3), 1462
(2026).
doi:10.1364/boe.583874
Ravaioli C, Mendez C, Gantner S, Ben Bader S, Witthauer L.Radar-Based Monitoring for Non-Contact Detection of Nocturnal Hypoglycemia in Diabetes: A Review.IEEE Journal of Biomedical and Health Informatics 30(8), 7058-7071
(2026).
doi:10.1109/jbhi.2026.3663452
Pleus S, Eichenlaub M, Eriksson Boija E, Fokkert M, Hinzmann R, Jendle J, Klonoff DC, Makris K, Nichols JH, Pemberton J, Selvin E, …, Witthauer L, et al.The Need for Standardization of Continuous Glucose Monitoring Performance Evaluation: An Opinion by the International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Continuous Glucose Monitoring.Journal of Diabetes Science and Technology 20(1), 201-206
(2026).
doi:10.1177/19322968241296097
Mendez C, Kaykayoglu CA, Bähler T, Künzler J, Lizoain A, Rothenbühler M, Schmidt MH, Laimer M, Witthauer L.Toward Detection of Nocturnal Hypoglycemia in People With Diabetes Using Consumer-Grade Smartwatches and a Machine Learning Approach.Journal of Diabetes Science and Technology 20(4), 1266-1275
(2026).
doi:10.1177/19322968251319800
Eiswirth ME, Resl M, Kulzer B, Roos T, Trümpy C, Balmer ML, Witthauer L, Mader JK, Diem P, Heinemann L, Ehrmann D, Hermanns N.Use of Continuous Glucose Monitoring and Insulin Pump Technologies in People With Type 2 Diabetes: Insights From a Survey of Health Care Professionals and Patients in Germany, Austria, and Switzerland.Journal of Diabetes Science and Technology 20(4), 1070-1079
(2026).
doi:10.1177/19322968261444041
2025
Hassanpour E, Nasehi M, Meymandinezhad A, Witthauer L.A low-power approach to optical glucose sensing via polarisation switching.Scientific Reports 15(1), 14200
(2025).
doi:10.1038/s41598-025-99367-0
Pleus S, Freckmann G, Slingerland RJ, Diem P, Eriksson Boija E, Fokkert M, Hinzmann R, Jendle J, Klonoff DC, Lu J, Makris K, …, Witthauer L, et al.Comparator Value Pairing Impacts Reported Continuous Glucose Monitoring System Accuracy.Journal of Diabetes Science and Technology 19(5), 1423-1426
(2025).
doi:10.1177/19322968251344303
Witthauer L, Mendez C, Garcia‐Tirado J, Eichenlaub M, Waldenmaier D, Pleus S, Freckmann G.Discrepancies between current displayed and auto‐logged glucose values in FreeStyle Libre 3: Implications for clinical interpretation.Diabetes, Obesity and Metabolism 27(12), 7367-7373
(2025).
doi:10.1111/dom.70140
Pleus S, Eichenlaub M, Eriksson Boija E, Diem P, Fokkert M, Hinzmann R, Jendle J, Klonoff DC, Makris K, Nichols JH, Pemberton J, …, Witthauer L, et al.Proposed minimum requirements for market approval of continuous glucose monitoring (CGM) systems: A viewpoint from the IFCC working group on CGM.Diabetes, Obesity and Metabolism 27(7), 4039-4042
(2025).
doi:10.1111/dom.16420
Freckmann G, Pleus S, Eichenlaub M, Eriksson Boija E, Fokkert M, Hinzmann R, Jendle J, Klonoff DC, Makris K, Nichols JH, Pemberton J, …, Witthauer L, et al.Recommendations on the Collection of Comparator Measurement Data in the Performance Evaluation of Continuous Glucose Monitoring Systems.Journal of Diabetes Science and Technology 19(4), 1072-1081
(2025).
doi:10.1177/19322968251336221
2024
Eichenlaub M, Pleus S, Rothenbühler M, Bailey TS, Bally L, Brazg R, Bruttomesso D, Diem P, Eriksson Boija E, Fokkert M, Haug C, …, Witthauer L, et al.Comparator Data Characteristics and Testing Procedures for the Clinical Performance Evaluation of Continuous Glucose Monitoring Systems.Diabetes Technology & Therapeutics 26(4), 263-275
(2024).
doi:10.1089/dia.2023.0465
Nicolier C, Künzler J, Lizoain A, Kerber D, Hossmann S, Rothenbühler M, Laimer M, Witthauer L.Detection of hypoglycaemia in type 1 diabetes through breath volatile organic compound profiling using gas chromatography–ion mobility spectrometry.Diabetes, Obesity and Metabolism 26(12), 5737-5744
(2024).
doi:10.1111/dom.15944
Melmer A, Martin‐Niedecken AL, Wehrli W, Lüchinger P, Riederer Y, Scott S, Pickles J, Niedecken S, Flagmeier D, Villiger S, Jurt R, …, Witthauer L, et al.Effects of home‐based exergaming on cardio‐metabolic and cognitive health in physically inactive individuals.Diabetes, Obesity and Metabolism 26(6), 2267-2274
(2024).
doi:10.1111/dom.15540
Cascales JP, Roussakis E, Müller M, Witthauer L, Li X, Goss A, Keshishian H, Marks HL, Nguyen JQ, Kelley L, Evans CL.Optimization of Transcutaneous Oxygenation Wearable Sensors for Clinical Applications.Advanced Sensor Research 3(3), 2300126
(2024).
doi:10.1002/adsr.202300126
2023
Freckmann G, Eichenlaub M, Waldenmaier D, Pleus S, Wehrstedt S, Haug C, Witthauer L, Jendle J, Hinzmann R, Thomas A, Eriksson Boija E, Makris K, et al.Clinical Performance Evaluation of Continuous Glucose Monitoring Systems: A Scoping Review and Recommendations for Reporting.Journal of Diabetes Science and Technology 17(6), 1506-1526
(2023).
doi:10.1177/19322968231190941
Witthauer L, Roussakis E, Cascales JP, Goss A, Li X, Cralley A, Yoeli D, Moore HB, Wang Z, Wang Y, Li B, Huang CA, et al.Development and in-vivo validation of a portable phosphorescence lifetime-based fiber-optic oxygen sensor.Scientific Reports 13(1), 14782
(2023).
doi:10.1038/s41598-023-41917-5
Wearable technology to monitor transcutaneous oxygen and carbon dioxide partial pressure.Optical Sensors Proceedings Optica Sensing Congress 2023 Ais Fts Hise Sensors Es 2023
(2023).
Conference
2022
Experimental and numerical optimization of optical wearable devices to measure tissue oxygenation.Optics Infobase Conference Papers
(2022).
Conference
2021
A fiber-based sensor for the quantification of intramuscular oxygen.Optics Infobase Conference Papers
(2021).
Conference
Li X, Roussakis E, Cascales JP, Marks HL, Witthauer L, Evers M, Manstein D, Evans CL.Optimization of bright, highly flexible, and humidity insensitive porphyrin-based oxygen-sensing materials.Journal of Materials Chemistry C 9(24), 7555-7567
(2021).
doi:10.1039/d1tc01164b
Witthauer L, Cascales JP, Roussakis E, Li X, Goss A, Chen Y, Evans CL.Portable Oxygen-Sensing Device for the Improved Assessment of Compartment Syndrome and other Hypoxia-Related Conditions.ACS Sensors 6(1), 43-53
(2021).
doi:10.1021/acssensors.0c01686
Quantification of tissue oxygenation using an intensity-based wearable device and machine learning approaches.Optics Infobase Conference Papers
(2021).
Conference
SYSTEMS AND METHODS FOR TOURNIQUET OPERATION AND CONTROL.
Patent WO/2021/041006
(2021).
Patent
Wearable devices for remote monitoring of transcutaneous tissue oxygenation.Optics Infobase Conference Papers
(2021).
Conference
Wireless wearable device for detection of transcutaneous tissue oxygenation based on phase phosphorimetry.Optics Infobase Conference Papers
(2021).
Conference
Cascales JP, Greenfield DA, Roussakis E, Witthauer L, Li X, Goss A, Evans CL.Wireless Wearable Sensor Paired With Machine Learning for the Quantification of Tissue Oxygenation.IEEE Internet of Things Journal 8(24), 17557-17567
(2021).
doi:10.1109/jiot.2021.3081044